|
Topic |
Research, Design, and Development |
Demonstration: Pilots and Modular Deployment |
Integration and Production Deployment |
|---|---|---|---|
|
LIMS and Workflow Management Participate in GTL cross-facility LIMS working group |
Available LIMS technologies Process description for LIMS system Crosscutting research into global workflow management systems Expert system approaches to guiding production protocols |
Prototype production design strategy system Prototype protein production LIMS system Prototype biochemical characterization LIMS system Workflow management system for production and characterization Process simulation for facility workflow |
Production design Protein production LIMS system Biochemical characterization LIMS system |
|
Data Capture and Archiving Participate in GTL cross-facility working group for data representation and standards |
Data models for process metadata and biophysical characterization data Technologies for large-scale storage and retrieval Preliminary designs for databases |
Prototype storage archives Prototype user-access environments |
Archives for key large-scale data types (e.g., biophysical characterization data) Archives linked to this facility's community databases and other GTL data resources Archives for microbial genome annotation with partners |
|
Data Analysis and Reduction Participate in GTL cross-facility working group for data analysis and reduction |
Algorithmic methods for biophysical characterization modalities Grid and high-performance algorithm codes Design for biophysical characterization tools library |
Prototype biophysical characterization tools library Prototype analysis grid for biophysical characterization, with partners Analysis tools linked to data archives |
Large-scale annotation systems with partners Production-analysis pipeline for biophysical characterization on grid and high-performance platforms Library with production-analysis codes Analysis tools pipeline linked to end-user problem-solving environments |
|
Modeling and Simulation Participate in GTL cross-facility working group for modeling and simulation |
Existing technologies explored for protein-fold prediction Technologies explored for low-resolution modeling from scattering data |
Genome-scale protein-fold prediction, with partners Prototype code for protein modeling from scatting data |
Production pipeline and end-user interfaces for genome-scale fold prediction Production codes for scattering-data modeling |
|
Community Data Resource Participate in GTL cross-facility working group for serving community data |
Data-modeling representations and design for databases: protein and reagent catalog, protein biophysical characterization, protein-production methods, and protocols |
Prototype database End-user query and visualization environments Databases integrated with other GTL resources and databases |
Production databases and mature end-user environments Integration with other GTL data resources Integration with other community protein-data resources |
|
Computing Infrastructure Participate in GTL cross-cutting working group for computing infrastructure |
Analysis, storage, and networking requirements for protein production facility Grid and high-performance approaches for large-scale data analysis for biophysical characterizations and establish requirements |
Hardware solutions for large-scale archival storage Networking requirements for large-scale grid-based biophysical data analysis |
Production-scale computational analysis systems Web server network for data archives and workflow systems Servers for community data archive databases |