|
Objectives Subtopics |
Research |
Pilots |
Production |
Products |
|---|---|---|---|---|
|
Affinity-Reagent Library Development |
Useful molecular scaffolds developed Useful libraries constructed and evaluated Design validated Expression tested System compatibility tested |
Automate library Protocol standards QA, standards |
Scale up |
Affinity reagents Reagent chips Protocols QA, standards |
|
Affinity-Screen Automation |
Develop protocols |
Scale up to 2k/year Protocol standards QA, standards |
Scale up to 25k/year |
Affinity reagents Reagent chips Protocols QA, standards |
|
Affinity-Reagent Target Design |
Novel vectors Validate designs |
Integrate into protein production system Protocol standards QA, standards |
Scale up |
Immobilized targets Protein chips Protocols QA, standards |
To develop and incorporate the necessary technologies and methods into a high-throughput production environment, a phased process will be followed as described in this roadmap. The process includes research, design, and development; modular and pilot-scale deployment; and final integration and scaleup into operational procedures.