Genomic Science Program

Research Highlights

The vision and scope of the Genomic Science program encompasses research and technology projects from diverse scientific disciplines, attracting broad interest and support from researchers at universities, DOE national laboratories, and industry. The program's challenge to the scientific community remains the further development and use of a broad array of innovative technologies and computational tools. These resources are needed to systematically leverage the knowledge and capabilities gained in DNA sequencing projects and bring us a step closer to biology-based solutions for important national energy and environmental needs. Highlights of progress in selected projects follow.

The Termite Gut: Nature’s Microbial Bioreactor for Digesting Wood and Making Biofuels

Metagenomics: Opening a New Window onto Natural Microbial Communities

• Microbial Community Thriving in Acid Mine Drainage
• Snapshot of the Complex Microbial Communities in the Sargasso Sea

Transfer of Photosynthetic Genes Between Bacteria and Phages

Measuring Differential Expression of Cytochromes in the Metal-Reducing Bacterium Geobacter

New Imaging and Computational Tools Enable Investigations of Carbon Cycling in Marine Cyanobacteria

Genetic Regulation in Bacteria

Capturing and Characterizing Protein Complexes, the Workhorses of the Cell

Synechococcus Encyclopedia: Integrating Heterogeneous Databases and Tools for High-Throughput Microbial Analysis

The Shewanella Federation

• Combining Computational and Experimental Approaches to Enhance Shewanella Genome Annotation
• Physiologic, Genetic, and Proteome Response of Shewanella oneidensis to Electron Acceptors

Bacteria Use “Nanowires” to Facilitate Extracellular Electron Transfer

• Shewanella
• Geobacter

Harvesting Electricity from Aquatic Sediments with Microbial Fuel Cells