Genomic Science Program

2001 DOE Genome Research in Support of the Genomic Science Program

• In FY2001, the U.S. Department of Energy Office of Biological and Environmental Research and Office of Advanced Scientific Computing Research called for new research that was to become the predecessor of the Genomic Science Program. The following projects were funded from these solicitations and are part of the Genomic Science Program.
  
  • Jim Fredrickson (PNNL), Jizhong Zhou (ORNL), and Eugene Kolker (BIATECH) for Environmental Sensing, Metabolic Response and Regulatory Networks in the Respiratory Versitile Bacterium Shewanella
  • Harley McAdams (Stanford) for Global Characterization of Genetic Regulatory Circuitry Controlling Adaptive Metabolic Pathways
  • Derek Lovley (U Mass Amherst) for a Conceptual and In Silico Model of the Dissimilatory Metal-Reducing Microorganism, Geobacter sulforeducens
  • Michael Daly (Uniformed Services University of the Health Sciences) for the Dynamics of Cellular Processes in Deinococcus radiodurans
  • Robert Tabita (Ohio State) for the Rhodopseudomonas palustris Microbial Cell Project, to study Rhodopseudomonas palustris
  • Timothy Donohue (University of Wisconsin-Madison) for the Molecular Basis for Metabolic and Energetic Diversity
  • John Leigh (University of Washington) for Global Regulation in the Methane Producing Archaeon Methanococcus maripaludis
  • Willem Vermaas (Arizona State University) for An Integrative Approach to Energy, Carbon, and Redox Metabolism in the Cyanobacterium Synechococcus
  • Norman Dovichi (University of Washington) for the Single-Cell Proteome Project: Ultrasensitive Proteome Analysis of Deinococcus radiodurans
  • Kenneth Downing (LBNL) for Electron Tomography of Microbial Cells
  • Gary Andersen (LLNL) for Pangenomic Analysis Using RDA
  • David Case (Scripps Research Institute) for Biomolecular Simulation Using Amber and CHARMM
  • Peter Ortoleva (Indiana University) for Cyber Cell: Automated Physico-Chemical Cell Model Development Through Information Technology
  • Andrey Rzhetsky (Columbia University) for Computational Analysis and Simulation of Bacterial Molecular Networks
  • Albert Laszio Barabasi (University of Notre Dame) for Organization of Complex Metabolic Networks
  • Julie Mitchell, (University of California, San Diego) for Parallel Protein Docking and Interaction Dynamics with Adaptive Meash Solutions to the Poisson-Boltzmann Equation
  • Michael Colvin (Lawrence Livermore National Laboratory) for Advanced Molecular Simulations of E. coli Polymerase III
  • Haluk Resat (Pacific Northwest National Laboratory) for Computational Approaches and Framework for Microbial Cell Simulations
  • T.P. Straatsma (Pacific Northwest National Laboratory) for Molecular Modeling of Complex Enzymatic reactions: The Respiratory Enzyme Flavocytochrome c3 Fumarate Reductase of Shewanella frigidimarina
  • Christopher Schilling (Genomatica, Inc.) for Development of the Next Generation of Genome-scale Constraints-Based Cellular Models
  • Eugene Kolker (BIATECH) for Interdisciplinary Study of Shewanella putrefaciens MR-1's Metabolism and Metal Reduction